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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 3
2003 1
2004 1
2005 4
2006 1
2007 2
2008 1
2009 1
2010 2
2011 2
2013 5
2014 2
2015 2
2016 2
2018 2
2019 2
2020 3
2023 2
2024 0

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35 results

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Page 1
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.
Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N. Miraoui H, et al. Am J Hum Genet. 2013 May 2;92(5):725-43. doi: 10.1016/j.ajhg.2013.04.008. Am J Hum Genet. 2013. PMID: 23643382 Free PMC article.
Among the >15 genes implicated in these conditions, mutations in FGF8 and FGFR1 account for ~12% of cases; notably, KAL1 and HS6ST1 are also involved in FGFR1 signaling and can be mutated in CHH. We therefore hypothesized that mutations in genes encoding a broade …
Among the >15 genes implicated in these conditions, mutations in FGF8 and FGFR1 account for ~12% of cases; notably, KAL1 and HS6ST …
Fibroblast growth factor signalling in osteoarthritis and cartilage repair.
Xie Y, Zinkle A, Chen L, Mohammadi M. Xie Y, et al. Nat Rev Rheumatol. 2020 Oct;16(10):547-564. doi: 10.1038/s41584-020-0469-2. Epub 2020 Aug 17. Nat Rev Rheumatol. 2020. PMID: 32807927 Review.
Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct development and homeostasis of articular cartilage, as evidenced by the fact that aberrant FGF signalling contributes to the maldevelopment of joints and to the onset and progression of osteoart …
Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct development and homeostasis of articular cartilage, as …
Estrogen-Induced Stromal FGF18 Promotes Proliferation and Invasion of Endometrial Carcinoma Cells Through ERK and Akt Signaling.
Wu J, Tao X, Zhang H, Yi XH, Yu YH. Wu J, et al. Cancer Manag Res. 2020 Aug 4;12:6767-6777. doi: 10.2147/CMAR.S254242. eCollection 2020. Cancer Manag Res. 2020. PMID: 32801905 Free PMC article.
To determine the effective receptors and detailed downstream signaling of FGF18, we co-cultured estrogen-treated hESCs with FGFR1-, FGFR2-, FGFR3- or FGFR4-knockdown Ishikawa cells. ...The FGF18-FGFR2 and FGF18-FGFR3 pathways had close correlations wit …
To determine the effective receptors and detailed downstream signaling of FGF18, we co-cultured estrogen-treated hESCs with FGFR1 …
FGF/FGFR1 system in paired breast tumor-adjacent and tumor tissues, associations with mammographic breast density and tumor characteristics.
Boraka Ö, Klintman M, Vallon-Christersson J, Zackrisson S, Hall P, Borgquist S, Rosendahl AH. Boraka Ö, et al. Front Oncol. 2023 Jul 20;13:1230821. doi: 10.3389/fonc.2023.1230821. eCollection 2023. Front Oncol. 2023. PMID: 37546410 Free PMC article.
FGF ligand expression was obtained from RNA-sequencing data for 327 of the included patients. RESULTS: FGFR1 levels were differently expressed in tumor-adjacent and tumor tissues, with increased FGFR1 levels detected in 58% of the tumors. ...While no clear associati …
FGF ligand expression was obtained from RNA-sequencing data for 327 of the included patients. RESULTS: FGFR1 levels were differently …
FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors.
Liu A, Li JY, Bromleigh C, Lao Z, Niswander LA, Joyner AL. Liu A, et al. Development. 2003 Dec;130(25):6175-85. doi: 10.1242/dev.00845. Epub 2003 Nov 5. Development. 2003. PMID: 14602678
This result is consistent with Fgf17 and Fgf18 being expressed in the midbrain and not just in r1 as Fgf8 is. ...As Fgf17 and Fgf18 are co-expressed with Fgf8 in many tissues, our studies have broad implications for how these FGFs differentially control development. …
This result is consistent with Fgf17 and Fgf18 being expressed in the midbrain and not just in r1 as Fgf8 is. ...As Fgf17 and Fgf1 …
Correlation of the SNPs of FGFR1, FGF10, FGF18 with nonsyndromic cleft lip with or without palate in Chinese population.
Wan WD, Yang SL, Liu JY, Cui YG, Zhou XP, Guo FF, Cheng HY, Cheng L, Xiao PF, Lu ZH. Wan WD, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2009 Aug 18;41(4):409-13. Beijing Da Xue Xue Bao Yi Xue Ban. 2009. PMID: 19727229 Free article.
OBJECTIVE: To explore the relationship between the polymorphisms in gene FGFR1, FGF10, FGF18 and the nonsyndromic cleft lip with or without cleft palate (NS CLP) in Chinese population. ...TDT, HRR and FBAT were also no significant difference. CONCLUSION: Our studies …
OBJECTIVE: To explore the relationship between the polymorphisms in gene FGFR1, FGF10, FGF18 and the nonsyndromic cleft lip wi …
A review of FGF signaling in palate development.
Weng M, Chen Z, Xiao Q, Li R, Chen Z. Weng M, et al. Biomed Pharmacother. 2018 Jul;103:240-247. doi: 10.1016/j.biopha.2018.04.026. Epub 2018 Apr 24. Biomed Pharmacother. 2018. PMID: 29655165 Review.
Here we try to review recent progress toward a detailed understanding of FGF signaling including FGF7, FGF8, FGF9, FGF10, FGF18 and their receptors FGFR1, FGFR2 in palate development studies and discuss how they interact with other factors on the basis of animal stu …
Here we try to review recent progress toward a detailed understanding of FGF signaling including FGF7, FGF8, FGF9, FGF10, FGF18 and t …
Infigratinib, a selective FGFR1-3 tyrosine kinase inhibitor, alters dentoalveolar development at high doses.
Michel ZD, Aitken SF, Glover OD, Alejandro LO, Randazzo D, Dambkowski C, Martin D, Collins MT, Somerman MJ, Chu EY. Michel ZD, et al. Dev Dyn. 2023 Dec;252(12):1428-1448. doi: 10.1002/dvdy.642. Epub 2023 Jul 12. Dev Dyn. 2023. PMID: 37435833
BACKGROUND: Fibroblast growth factor receptor-3 (FGFR3) gain-of-function mutations are linked to achondroplasia. Infigratinib, a FGFR1-3 tyrosine kinase inhibitor, improves skeletal growth in an achondroplasia mouse model. ...RESULTS: Mandibular third molars were reduced i …
BACKGROUND: Fibroblast growth factor receptor-3 (FGFR3) gain-of-function mutations are linked to achondroplasia. Infigratinib, a FGFR1 …
Anti-Cancer Effect of Cordycepin on FGF9-Induced Testicular Tumorigenesis.
Chang MM, Hong SY, Yang SH, Wu CC, Wang CY, Huang BM. Chang MM, et al. Int J Mol Sci. 2020 Nov 6;21(21):8336. doi: 10.3390/ijms21218336. Int J Mol Sci. 2020. PMID: 33172093 Free PMC article.
Our novel finding from microarray analysis of cordycepin-treated MA-10 mouse Leydig tumor cells is that cordycepin down-regulated the mRNA levels of FGF9, FGF18, FGFR2 and FGFR3 genes in MA-10 cells. Meanwhile, the IPA-MAP pathway prediction result showed that cordycepin i …
Our novel finding from microarray analysis of cordycepin-treated MA-10 mouse Leydig tumor cells is that cordycepin down-regulated the mRNA l …
Fibroblast growth factor control of cartilage homeostasis.
Ellman MB, Yan D, Ahmadinia K, Chen D, An HS, Im HJ. Ellman MB, et al. J Cell Biochem. 2013 Apr;114(4):735-42. doi: 10.1002/jcb.24418. J Cell Biochem. 2013. PMID: 23060229 Free PMC article. Review.
Recent evidence suggests that FGF-2 selectively activates FGF receptor 1 (FGFR1) to exert catabolic effects in human articular chondrocytes and IVD tissue via upregulation of matrix-degrading enzyme production, inhibition of extracellular matrix (ECM) accumulation and prot …
Recent evidence suggests that FGF-2 selectively activates FGF receptor 1 (FGFR1) to exert catabolic effects in human articular chondr …
35 results